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Further research must be conducted on the additional potential benefits of DPP-4 inhibitors before the recommendation for DPP-4 inhibitors over SGLT2 inhibitors or GLP-1 agonists as a second-line agent for patients with type 2 diabetes can be strengthened

And importantly, if unintended weight loss occurs in a lean patient, we stop or lower the dose

Moreover, bone microarchitecture/strength changes assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT) are lacking

Materials and methods Data source The FDA Adverse Event Reporting System (FAERS), maintained by the U.S

Table of Contents Common and Emerging Skin Reactions Timing, Mechanisms, and Severity Patterns When to Discontinue Therapy Referral and Management Considerations Conclusion FAQ Common and Emerging Skin Reactions Injection-site reactions remain the most frequently reported skin-related side effects of GLP-1 medications