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While adverse event reports do not establish causation (the events may have been caused by factors unrelated to the compounded medication), the volume of reports signals a need for heightened caution

Effects of renal impairment on the pharmacokinetics of the dual GIP and GLP-1 receptor agonist tirzepatide

Clinical trials of semaglutide in non-MTC populations showed no increased thyroid cancer risk
Treating these conditions costs a lot of money, and its clear that weight loss can significantly reduce these risks

But here's another important caveat: This study only looked at short-term effects