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[4] For weight management, clinically meaningful weight loss is generally defined as 5% or more of initial body weight

If you suspect an adverse reaction to a GLP-1 medication, report it to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

BMJ Group and Pharmaceutical Press: London, 2020

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Direct answer: If insurance denies coverage, patients usually face high out-of-pocket costs unless they use a savings program, an appeal pathway, or a different treatment plan