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The first involved GLP-1 (7-37) synthesized by Mojsov, which was overseen by David Nathan, a physician and director of the Diabetes Clinic at MGH

New therapies are expanding, populations are ageing and demand keeps rising

Off-Label Use and Social Media Hype The increasing use of GLP-1 medications for cosmetic weight lossespecially among people without obesity or diabetesraises ethical and medical concerns

In summary, GLP-1 (and possibly GIP/GLP-1) receptor agonists could improve asthma outcomes through weight reduction, decreased airway inflammation and mucus secretion, decreased type 2 inflammation signaling, reduction in IL-4, 5, 13, and 33 secretion, reduced mast cell activity, as well as increases in surfactant production and smooth muscle relaxation [57]