retatrutide recommended dosage clinical trials VisualAbstract: reduces body weight by 17.5% in patients with obesity Retatrutide for Weight Loss: TRIUMPH-1
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The first-in-class injectable could be the next big thing in diabetes and obesity treatment.

Tirzepatide (Zepbound/Mounjaro): A dual GLP-1/GIP receptor agonist undergoing evaluation for MASH after demonstrating significant liver fat reduction in studies.Retatrutide: A "triple agonist" targeting GLP-1, GIP, and glucagon (GCGR) receptors, which has shown "unprecedented" efficacy in weight loss and is being evaluated for metabolic diseases including MASH

GLP-1 RA use demonstrated significantly higher rates of GRC compared to non-users (OR: 5.57

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