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Tirzepatide is not approved for use in type 1 diabetes or for the treatment of diabetic ketoacidosis

GLP-1 RAs could inhibit the expression of plasminogen activator inhibitor type-1 (PAI-1) and vascular adhesion molecule (VAM) in human vascular endothelial cells in vitro, which had a protective effect against endothelial cell dysfunction (ECD) in the early stages of diabetic vascular disease [32] and might explain the lower incidence of background and severe nonproliferative DR among individuals who used GLP-1 RAs

Yes, GLP-1 therapy can improve sleep quality in adults

However, if a patient needs metabolic or blood testing, they can go to a local lab

Consistent with this recommendation, the FDA also advises withholding SGLT2 inhibitors for three days [20, 21]