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In animal models SGLT2 inhibitors have been theorized to potentially increase risk of MTC

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Preclinical Studies In preclinical trials, retatrutide was administered to male mice models with obesity [42]

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West, S., Scragg, J., Aveyard, P., Oke, J

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F., & STEP 1 Study Group (2021)

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For instance, retrospective analyses have suggested potential associations with thyroid cancer risk during long-term use [4], whereas studies of pancreatic cancer have yielded contrasting results [6,7,8]

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