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Canada GLP-1 Agonists Weight Loss Drugs Market Estimates and Forecasts, 2018-2030 (USD Million) 7.2.4

Common adverse effects , particularly during dose escalation, include: Nausea (reported by 2050% of patients, usually mild to moderate) Vomiting, diarrhoea, or constipation Abdominal discomfort or bloating Reduced appetite (therapeutic effect, but may feel unusual initially) Fatigue or headache These effects typically diminish over several weeks as tolerance develops

Logging symptoms as they happen helps put nausea, fatigue or appetite changes into context, especially during titration, when doses are being adjusted
Sitagliptin and Liraglutide Modulate L-dopa Effect and Attenuate Dyskinetic Movements in Rotenone-Lesioned Rats

GI = gastrointestinal