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Composition Cagrilintide: 5mg GLP-1 S: 5 mg Fill volume: 2 ml vial Appearance: lyophilized powder in a sealed research vial Research Focus (non-clinical) Combined pathway evaluation of amylin-receptorrelated and GLP-1receptor mechanisms in in-vitro or ex-vivo models Assay development, including chromatographic separation of two co-formulated peptides and blend ratio characterization Stability characterization of a two-analyte lyophilized blend under laboratory storage conditions Method documentation for HPLC/LC-MS identity and purity assessments Documentation COA pending third-party verification in progress Important Notice For research use only Not for human consumption Not intended to diagnose, treat, cure, or prevent any disease Quality & Manufacturing COA pending third-party verification in progress Lyophilized for transit stability

Conclusion The population pharmacokinetic study showed that semaglutide exposure is not affected by covariates other than body weight at either a maintenance dose of 0.5 or 1.0 mg semaglutide