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The main adverse events associated with GLP-1 receptor agonists are gastrointestinal (GI) in nature, primarily nausea, vomiting, and diarrhea (Table 2)

These are self-injected once a week, usually in the abdomen or thigh, using a pre-filled syringe or auto-injector

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The effects on delayed gastric emptying, satiety, and decreased caloric intake can promote weight loss

Zepbound and Mounjaro prescribing information also describe delayed gastric emptying with tirzepatide
