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Gut hormone release and appetite regulation in healthy non-obese participants following oligofructose intake

Article Information Published Online: June 10, 2025

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A recent meta-analysis of 14 RCTs in adolescents with overweight or obesity (including those with type 2 diabetes) confirmed that GLP-1 RA therapy led to mean HbA1c reductions (0.34% risk difference) and weight loss (4.3 kg) relative to the control group (34)

The clinical evidence shows most people stay on semaglutide for at least 68 weeks to achieve significant weight loss
