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Outcomes commonly tracked included low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, fasting plasma glucose, insulin, systolic and diastolic blood pressure, C-reactive protein (CRP, an inflammation biomarker), and salivary immunoglobulin A (IgA, an immune biomarker)

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Lixisenatide and cardiovascular outcomes The first trial which evaluated lixisenatide, published in 2016, was the Evaluation of Lixisenatide in Acute Coronary Syndrome trial which included 6068 patients with T2DM who had sustained an acute coronary event within 180 days before randomization

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