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In a previous cohort study comparing GLP-1RAs with anti-obesity medications bupropion-naltrexone in patients with obesity who had no T2DM [45] showed an increased risk of bowel obstruction

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Ressalta-se que a escolha deve levar em considerao aspectos individuais do paciente, como idade, peso, nveis da glicose sangunea (jejum e ps-prandial) e aspectos clnicos indicativos de resistncia ou deficincia insulnica como mecanismo fisiopatolgico predominante