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Improvements in 5-HT production occur by increasing EC expression of tryptophan hydroxylase, the rate-limiting enzyme in EC 5-HT production 288 , or by increasing microbial metabolites, such as SCFAs and BAs, that are known to stimulate EC 5-HT production 74

Both trials suggest maintenance strategies, such as lower-dose injections or oral therapies, could offer patients more flexible, potentially more convenient options for sustaining weight loss after intensive treatment

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[DOI] [PubMed] [Google Scholar] 50.Correll C.U., Lencz T., Malhotra A.K

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