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The GLP-1 market has faced supply constraints in recent months as drugs like Ozempic and Wegovy continue to skyrocket in popularity.

However, the coexistence of micro and macrovascular disease is associated with the highest cardiovascular risks which highlights the importance that pharmacological treatment of type 2 diabetes mellitus provides not only glycemic control, but also cardiovascular safety

Not for Use in Diagnostic Procedures.

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report here on a GIPR antagonist conjugated to GLP-1 analogues that reduces body weight and improves metabolic markers in preclinical and phase 1 clinical settings.