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Histological improvement alone is no longer sufficient: we must determine whether treatment restores the patients metabolic architecture and simultaneously reduces hepatic, cardiovascular, and renal risk

This is a complication of diabetes with high blood sugar, breathing difficulty, confusion, excessive thirst, a sweet smell to the breath or a sweet or metallic taste in the mouth

The SURMOUNT-4 trial demonstrated 25.3% total body weight loss over 88 weeks in the treatment continuation group

Black patients with HER2+ breast cancer treated with trastuzumab are more likely to develop LV dysfunction than White counterparts, even after controlling for age, disease state, and cardiovascular risk factors
