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Always consult your healthcare provider before starting, stopping, or changing any medication

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TABLE 1 Summary of the mechanisms of action and effects of GLP-1R agonists in AD

Thus far, 7 cardiovascular outcomes trials (CVTO) have produced robust data supporting the beneficial effect of GLP1RAs on major adverse cardiovascular events (MACE)

However, in isolated mouse hearts perfused with the sAC inhibitor KH7, we observed loss of cardioprotection with GLP-1(2836), but not GLP-1, as measured by LVDP at the end of the reperfusion (25.2 1.7 mmHg, n = 3, vs