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In vitro studies suggest that GLP-1 has effects on numerous renal cell populations, including glomerular endothelial cells

Weight reduction following RYGB and AGB in severely obese patients is associated with an increase in heart rate variability (119)

Diabetes Care (2005) 28(2):3238

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This multi-receptor targeting approach has shown enhanced effectiveness in glycaemic regulation and weight loss relative to single-receptor agonists, indicating a viable route for future pharmaceutical development
