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glp 1 tone Downregulation of the GLP-1/CREB/adiponectin pathway is partially responsible for diabetes-induced dysregulated vascular and VSMC dysfunction GLP-1 Receptor Agonists in Mood
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Front Endocrinol (Lausanne) 2018;9:672

Other studies have exposed rodents (rat, rabbit) to metformin in different metabolic models

Maturitas (2012) 71(3):24856

The clinical presentation of hypothyroidism reflects the consequences of a slowed metabolic rate: fatigue, weight gain, cold intolerance, constipation, dry skin, bradycardia, and, in some patients, depression

7 Walker, E., Lo, K., & Gopal, P
