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To be clear, studies suggest that GLP-1s generally lead to greater and faster weight loss results than relying solely on lifestyle changes like diet and exercise
Reduced-Frequency GLP1 Therapy Maintains Weight, Body Composition, and Metabolic Syndrome Improvements: A Case Series

This study demonstrated significant improvements in parameters such as HbA1c, body weight, and lipid profiles, along with a reduced need for rescue medications to control hyperglycemia (107), an effect that has been demonstrated again in other meta-analyses carried out subsequently (108)

How Metformin Works Metformin mainly acts on the liver to lower the production of glucose, which helps bring down blood sugar levels

it often improves as inflammation decreases and metabolic health improves
