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Your doctor may avoid prescribing GLP-1 agonists if you have a family history of medullary thyroid cancer

In TRIUMPH-1 the pivotal Phase 3 obesity trial, reported May 21, 2026 participants on the 12 mg dose lost an average of 28.3% of their body weight (70.3 lbs) at 80 weeks , versus 2.2% on placebo

You can keep pouring, but if sodium and potassium are leaking out through natriuresis and GI losses, the water will not stay where your body needs it