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A combination is often ideal for full restoration
Weight-loss drugs are not fertility drugs, and women should immediately stop taking them if they become pregnant, Narula cautioned
By hitting all three receptors, retatrutide aims for a larger impact than previous drugs that only target one or two
Concerns have also been raised about possible effects on the pancreas and thyroid
A 2025 preprint showed semaglutide users were about 50% more likely to receive a hair-loss diagnosis than users of Contrave again pointing to an indirect mechanism
