glp-1 hormone drugs protect brain health by improving neurovascular function and reducing inflammation GLP-1 Medications – Community Education

P5 showed a greatly diminished efficacy and potency ( E max =29 and 32%

[DOI] [PubMed] [Google Scholar] 97.Vanderheyden M, Bartunek J, Goethals M, Verstreken S, Lambeir AM, De Meester I, et al

On average, patients may lose 5-10% of their body weight within this timeframe

Typical Retail Pricing Understanding Ro's pricing relative to standard retail: Wegovy Retail Pricing (without insurance or savings): Typical Retail : $1,300-$1,400+ per month Ro Cash-Pay : $499/month via NovoCare Savings : ~$800-900/month (~64% reduction) Zepbound Retail Pricing (pens, without insurance): Typical Retail : $1,050-$1,100+ per month Ro Vials via LillyDirect : $349-$499/month Savings : ~$550-750/month (~66% reduction at maintenance dose) Important Context : Retail pricing represents list prices that few individuals pay

Conclusions: The current evidence for the role of GLP-1RAs as a potential anti-inflammatory therapy in IBD is limited, but provides the impetus for much-needed prospective studies and RCTs that include patients with active IBD