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Summary Together, these findings demonstrate that elevated glucose results in actin polymerization that impedes both phases of biphasic insulin secretion, and that GLP-1 can restore glucose sensitivity and promote insulin release by correcting errors in actin dynamics at both phases

These hormones work in a complex, finely tuned interplay to regulate the menstrual cycle, including ovulation and the shedding of the uterine lining during menstruation

Ther Adv Drug Saf 2012;3(4):157164

Tirzepatide: GI side effects common but well-characterized
