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Monotherapy showed higher AE rates
Additionally, critical factors that shape the relationship between GLP-1RAs and cancer risk are thoroughly analyzed, including patient demographics, comorbidities, treatment regimens, and lifestyle factors, offering essential insights for developing individualized treatment protocols
Initially developed to improve glycemic control, these agents are now recognized as important components of cardiovascular risk reduction strategies
Four study groups were established: all GLP-1RA users, SGLT2i users, insulin users and other glucose-lowering agent users (miscellany group)
Alarmingly, this trend is growing and increasingly affecting younger populations at an accelerating rate [2]
