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LillyDirect's self-pay program sells brand Zepbound vials starting at $299 per month (maintenance pricing varies by dose), which has become the standard fallback for Aetna members whose plans deny coverage

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Without insurance, list prices in 2026 are roughly: Wegovy $1,349 per month, Zepbound $1,086 per month (auto-injector) or $349 to $549 (vials through LillyDirect), Ozempic $998 per month, Mounjaro $1,069 per month