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Understanding these pathways helps explain why these medications consistently lower blood pressure across different patient populations
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In accordance, GLP-1RAs increase microvascular blood flow in muscle tissue, resulting in increased myocyte metabolism, increased muscle mass and muscle atrophy inhibition [182]

other intestinal hormones such as GIP, PYY, Neurotensin, INSL-5 or the GIP co-secreted Xenin (217) might play an important role (Figure 2)

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