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A significant difference was found also in TBUT between the two groups (median 10 sec, range 6.717, 95% CI: 10.211.7 vs median 5.85 sec, range 111, 95% CI: 4.67.2 respectively

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It is important to note that, in patients with long-standing diabetes and insufficient insulin secretory capacity, the glucose-lowering efficacy of GLP-1 RA is likely to be reduced as a result of diminished incretin effects, and concomitant basal insulin treatment may be required [53]

Monitoring these side effects ensures that the medications are working effectively and safely