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Injectables can be difficult to stick with over the long term: People get sick of the shots, they might find it hard to stay on top of a once-weekly injection, they dont want to have to worry about refrigeration when traveling, etc

289 , 1896618977 (2014) Venkatakrishnan, A

By contrast, MACE risk was significantly lower among those who continued GLP-1RA use for 2 and 2.5 years, and lowest among those who maintained treatment for three years

5.2 Oxyntomodulin as an endogenous polypharmacologic signal As discussed in Section 4.4, it also plays a central role in appetite regulation in the context of metabolic peptides

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