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Briefly, 0.5 mg of labeling dye was dissolved in 50 l DMSO and was slowly added to 1 ml of protein (10 mg/ml) in 0.1 M sodium bicarbonate buffer (pH 8.3)

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doi:10.1007/s40265-022-01746-8 77

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In that same trial, 100% of participants in the 8 mg group lost at least 5% of their body weight

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