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Description
Fatigue appears in 8-12% of users, though distinguishing medication-induced fatigue from diet-related energy deficits proves difficult

Source: Hwang, et al JAMA Health Forum March 14, 2025 Implications for employers: This modeled study suggests that employers should at least offer access to the two combination generic medications for obesity if budgets allow

Loureno et al
23 The most commonly used off-label medicine is acetazolamide

These typically subside as dosing stabilizes
