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Deconstructing networks of p53-mediated tumor suppression in vivo
Drakos E, Atsaves V, Li J, Leventaki V, Andreeff M, Medeiros LJ, et al
"Treatment" of sad emotional states with nicotine over time may also impair innate restorative responses, just as treatment of chronic pain with opioids results in many patients experiencing hyperalgesia, a pathologically heightened response to painful stimuli
Like for many other cancers, mutations in p53 are common in lung cancer and certain hotspot mutants predominate
Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting
