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We believe that self-regulatory efforts have played and are playing a significant role in dealing with the issue [of cigarette advertising], and that the furtherance of such efforts should be encouraged. In mid-June, however, there was a development that showed these assurances in a different light, somewhat embarrassing to the broadcasting industry

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These enzymes include glutathione synthetase ( Gss ), which is crucial for glutathione ( Gsh ) production, and thioredoxin reductase 1 ( Txnrd1 ), which maintains thioredoxin in its reduced state (Bondareva et al., 2007