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In terms of inhibiting ferroptosis, small molecules such as Ferrostatin-1 and Liproxstatin-1 act by clearing lipid peroxyl radicals and stabilizing the membrane structure of PUFA, thereby inhibiting ferroptosis (258)

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Increased expression and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and NAD(P)H quinone dehydrogenase 1 (NQO-1) are typical mechanisms activated during OS and were detected in mouse primary brain microvascular endothelial cells after exposure to e-vapor extract [27], [101]

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