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Description
Future RCTs would need 3213 patients/group to test a hypothesis of 10% versus 8% failure, or 1356 patients/group to compare 10% versus 7% failure (stat.ubc.ca/~rollin/stats/ssize/b2.html, 80% power, p = 0.05)

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1, 1863, when President Abraham Lincoln issued his Emancipation Proclamation
