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In addition to using chemical enhancers, researchers have also investigated mechanical approaches to augment the permeability of drugs through the skin [35]

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According to Ohms law : V=IR Where: V= the voltage of potential difference (in volts (V)) I= the current (in amperes (A)) R= the resistance (in ohms) Movement of ions across a permeable cell membrane constitutes an electrical system, where current will occur, driven by the potential difference in the system and opposed by the systems resistance

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