melanotic macule skin Oral Macule: a small dark spot in the mouth AD :: Annals of Dermatology

Melanocytes originate from embryonic neuro-ectoderm, and are dispersed predominantly in the skin, but they can be found also in several other anatomical locations such as the cochlea of the ear, eye, adipose tissue, etc

The Supporting Information is available free of charge at Overview of preferred ionization modes and applications for various MALDI matrices, including small organic molecules, designed and synthesized organic matrices, common-used dopants, inorganic matrices, and organicinorganic binary/hybrid matrices, and the summaries of representative MALDI matrices for specific analytical fields, namely proteomics, metabolomics, lipidomics, glycomics, nucleic acid analysis, and quantitative analysis (PDF) R

doi: 10.1038/s12276-022-00757-5

Once that additional melanin has been produced, your body doesnt simply remove it overnight

Sagoe, D., McVeigh, J., Bjornebekk, A., Essilfie, M