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Pioneering research established that 4-HNE negatively regulates tumor cell growth by modulating the expression of oncogenes such as c-myc, c-myb, and c-fos, either independently or in conjunction with serum growth factors [116,117,118,119]

These cherry blossom extracts have been studied for their antioxidant properties and their ability to support balanced melanin activity, helping the skin maintain an even, healthy appearance over time These are complemented by rose bud petal extract, sourced from young rose buds at peak potency

doi: 10.3390/ijms26031226 455 FonsecaLRSilvaGRLusCardosoHJCorreiaSVazCVet al

failure reviews 13 , 393404, (2008)

Collectively, these findings suggest that targeting HADHA or SIRT1 may represent a potential therapeutic strategy for age-related HF