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Introduction Patients affected by chronic kidney disease (CKD) or end-stage renal disease (ESRD) have a shorter life expectancy than those with normal renal function, primarily due to the dramatic increase in cardiovascular mortality [1]

Wisconsin medical journal , 93(5), 203205

Myelin, just for clarification, is a protective and conductive sheath around nerves which relay signals (electrical impulses) throughout your nervous system

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They may appear gradually, with worsening intensity over time, or manifest suddenly in full force
