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The inherent peroxide bridge bonds present in the structure of ART have a propensity to interact with Ni 2+ ions, leading to the generation of free radicals that possess the capability to induce cell death in tumor cells

Dectin-3 deficiency promotes colitis development due to impaired antifungal innate immune responses in the gut

Additionally, we sought to demonstrate specificity of RSL3 for targeting BRAF/RAS addicted cancer cells by selecting TPC-1, a PTC cell line, that lacks RAS or BRAF mutations

Kinetic data were analysed in Excel and SigmaPlot 12 by non-linear and linear regression according to MichaelisMenten, LineweaverBurk, EadieHofstee and Hanes theory 11,12,18

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