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Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

This can be problematic for people with certain health conditions or older adults whose digestive efficiency may be compromised

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These numbers surpassed what most fat burning peptides achieve in animal research, and they caught the attention of researchers worldwide
