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CFS/FM/ME can be a debilitating condition affecting around 3% of the population The condition is generally misunderstood, however, symptoms are very similar to those seen with an absolute deficiency of vitamin B12 The condition is characterized by Paradoxical B12 deficiency Studies on over 700 individuals have shown all have functional B2 deficiency Functional B2 deficiency results in functional B12 deficiency

Effects of human growth hormone and its lipolytic fragment (AOD-9604) on lipid metabolism. Endocrinology, 2001

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Ignoring Displacement: Very advanced researchers might account for the volume displacement of the peptide powder itself, but for most applications with these quantities, it's a negligible factor