glutathione transdermal gel US8580742B2 - Topical formulations for menopausal skin ACS 200 Silver-Glutathione Gel Extra
Description
however, it is known to be only 50% absorbed into the systemic circulation

Increased expression of mrnas for il-4, il-17, il-22 and il-31 in skin lesions of subacute and chronic forms of prurigo
Soft Matter 2010

That reaction is completely human, and it is also, in most cases on testosterone replacement therapy, premature

This is a well-established physiological response
