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This does not mean everyone taking acid-suppressing medications will become deficient, but it does highlight the importance of monitoring nutritional status during prolonged use

Furthermore, in rats with an infrarenally occluded inferior caval vein (Vukojevic et al., 2018), we observed a particular expression pattern of the essential factors that modulate many genes and processes such as diverse proadhesive, proinflammatory, and prothrombotic genes upon vascular injury (Ansari, Ansari, Andersson, & AndrenSandberg, 2015

Rungoe C, Langholz E, Andersson M et al (2014) Changes in medical treatment and surgery rates in inflammatory bowel disease: a nationwide cohort study 19792011
Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study

In VERTOS II, rates of up to 72% were reported
