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Roca, M

Lipid peroxidation drives renal cyst growth in vitro through activation of TMEM16A

[33] In contrast to peripheral administration, when administered intranasally via a nasal spray, oxytocin reliably crosses the bloodbrain barrier and exhibits psychoactive effects in humans

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This regulation is achieved through Akt substrate of 160kDa (AS160) that produces cellular responses to both Akt and mTORC2 signals to regulate glucose transporter 4 (GLUT4) trafficking during insulin stimulation, and to maintain glucose homeostasis (161)
