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Psychiatry 6 , e976e976 (2016)

However, the p K a of the cysteine sulfhydryl side-chain is 8.4, and therefore, at intracellular pH ranges (7.07.4), these groups exist mostly in the non-nucleophilic thiol state

Insufficient ATP synthesis directly impairs muscle contraction and may accelerate fatigue progression (77)

This molecular explanation of ferroptotic cell death sets the stage for ferroptosis therapeutic strategies that not only act on lipid peroxidation, but that additionally target the executors of ferroptotic cell death: truncated PLs and LDEs
, 2020), and other recycling systems contribute to ascorbate recycling when ascorbate levels are high
