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Warnings and Precautions: Use caution when administering L-Carnitine Injection to patients with renal impairment, as accumulation of carnitine may occur

Blocking MR receptors and interfering with glucocorticoids stimulation of glutamate activity counteracted stress-induced suppression of the histone acetyltransferase p300 mRNA levels in the hippocampus, showing a link between glucocorticoids and epigenetic programming of the glutamatergic system [20]