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Antitumor effects in a glioblastoma mouse model All experiments were conducted in accordance with guidelines approved by the Animal Experimentation Ethics Committee of Kyoto Pharmaceutical University (Approval No.: A21-011-02)

A recent systematic review pointed out that the outcomes related to the effects of NAC on renal function are very variable, with a rate of positive results from the analyzed trials of 39% for oral NAC and 29% for IV NAC [9]