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To understand these discrepancies, it is important to note that autophagy involves dynamic and complicated processes, and it has been a challenge in autophagy research to capture a dynamic process with static measurements [66]

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discovered that pretreatment of losartan decreased the expression of nuclear factor kappa B (NF-B) and the activation of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription proteins (STATs) pathway, reducing the apoptotic ratio of cells through modulating phosphorylation and the leak of cytochrome C to the cytosol (Li C et al., 2017)

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