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Recent studies have shown that enzymes (e.g., DHCR7, MSMO1, CYP51A1, EBP, and SC5D) involved in distal cholesterol biosynthesis have been identified as having a critical role in the regulation of ferroptosis, with the ability to dictate the level of 7-dehydrocholesterol (7-DHC) [60, 61]

Instead of making unrealistic claims, it focuses on consistent care, which aligns better with long-term skin maintenance.

The Nrf2/HO-1 pathway plays a vital role in antioxidative and iron-homeostatic responses, exhibiting a well-documented double-edged sword effect in ferroptosis regulation

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Materials and methods Literature search and data extraction We performed a pooled analysis of published articles in PubMed,Embase, Web of Science, and CNKI database for studying the association between the MTHFR C677T variant and folate content and colorectal cancer